Dental Publication / Article Details |
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Histologic Effect of Pure-Phase Beta-Tricalcium Phosphate on Bone Regeneration in Human Artificial Jawbone Defects
Author(s):
Paolo Trisi, DDS, PhD;Walter Rao, MD, DDS; Alberto Rebaudi, MD, DDS; Peter Fiore, MD, DDS
Date Added:
7/28/2009
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Summary:
The effect of the pure-phase beta-tricalcium phosphate (beta-TCP) Cerasorb on
bone regeneration was evaluated in hollow titanium cylinders implanted in the
posterior jaws of five volunteers. Beta-TCP particles were inserted inside the
cylinders and harvested 6 months after placement. The density of the newly
formed bone inside the bone-growing chambers measured 27.84% ± 24.67% in
test and 17.90% ± 4.28% in control subjects, without a statistically significant difference.
Analysis of the histologic specimens revealed that the density of the
regenerated bone was related to the density of the surrounding bone. The present
study demonstrates the spontaneous healing of infrabony artificial defects,
2.5 mm diameter, in the jaw. The pure beta-TCP was resorbed simultaneously
with new bone formation, without interference with the bone matrix formation.
(Int J Periodontics Restorative Dent 2003;23:69–77.)
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